Aperiodic activity as a biomarker of seizures and neuromodulation

The aperiodic exponent was positively related to instantaneous and multidien disease state severity and negatively related to therapeutic stimulation. Aperiodic activity may emerge as a practical biomarker of disease state and treatment response to guide neuromodulation for epilepsy.

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Publication Details

Journal
Brain stimulation
Published
2025-04-03
DOI
https://doi.org/10.1016/j.brs.2025.03.022
Citations
7
Primary Topic
Neuroscience and Neuropharmacology Research
Type
article
Field-Weighted Citation Impact
6.36
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article

Aperiodic activity as a biomarker of seizures and neuromodulation

Lesley Kaye, David Satzer, John A. Thompson, Steven Ojemann et al.
7 citations
Brain stimulation
Neuroscience and Neuropharmacology Research
6.36
article

Aperiodic activity as a biomarker of seizures and neuromodulation

Lesley Kaye, David Satzer, John A. Thompson, Steven Ojemann, Daniel R. Kramer
article en
7 citations

Abstract

The aperiodic exponent was positively related to instantaneous and multidien disease state severity and negatively related to therapeutic stimulation. Aperiodic activity may emerge as a practical biomarker of disease state and treatment response to guide neuromodulation for epilepsy.

Brain stimulationVol. 18(3)
University of Chicago Medical Center (US), University of Colorado Anschutz Medical Campus (US)
Zero hunger
Openalex Percentile: Top 3%
Neuroscience and Neuropharmacology Research
6.36
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Aperiodic activity as a biomarker of seizures and neuromodulation — Lesley Kaye, David Satzer, et al. · Brain stimulation (2025) | TGRS Research Map | TGRS