Severe hypercalcemia as the initial presentation of renal cell carcinoma: a diagnostic case report

Prompt recognition of paraneoplastic hypercalcemia in RCC facilitates timely intervention. This case demonstrates the value of comprehensive diagnostic evaluation and multidisciplinary management combining supportive care with targeted immunotherapy. Further prospective studies are needed to optimize therapeutic strategies for patients presenting with metabolic derangements suggestive of underlying malignancy.

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Publication Details

Journal
Annals of Medicine and Surgery
Published
2025-04-03
DOI
https://doi.org/10.1097/ms9.0000000000003252
Primary Topic
Bone health and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Severe hypercalcemia as the initial presentation of renal cell carcinoma: a diagnostic case report

Daniel Bitetto, Amitabh Kumar Upadhyay, Shivani Modi, Naveen Gautam et al.
Annals of Medicine and Surgery
Bone health and treatments
article

Severe hypercalcemia as the initial presentation of renal cell carcinoma: a diagnostic case report

Daniel Bitetto, Amitabh Kumar Upadhyay, Shivani Modi, Naveen Gautam, Bal Krishna Subedi, Paul Baek
article en

Abstract

Prompt recognition of paraneoplastic hypercalcemia in RCC facilitates timely intervention. This case demonstrates the value of comprehensive diagnostic evaluation and multidisciplinary management combining supportive care with targeted immunotherapy. Further prospective studies are needed to optimize therapeutic strategies for patients presenting with metabolic derangements suggestive of underlying malignancy.

Annals of Medicine and SurgeryVol. 87(5)
Tribhuvan University (NP), Einstein Medical Center Montgomery (US)
Openalex Percentile: Top 90%
Bone health and treatments
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