Association between serum neurofilament light chain levels and grip strength among US adults: a cross-sectional study using National Health and Nutrition Examination Survey data from 2013 to 2014

Our study demonstrates a strong, negative and linear correlation between elevated serum NfL levels and grip strength. Notably, our findings indicate that individuals aged between 60 and 75 years, those with physical inactivity and those with CKD exhibit a more pronounced reduction in grip strength with increasing serum NfL levels.

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Publication Details

Journal
BMJ Open
Published
2025-04-01
DOI
https://doi.org/10.1136/bmjopen-2024-084766
Citations
3
Primary Topic
Child Nutrition and Feeding Issues
Type
article
Field-Weighted Citation Impact
4.41
Controls
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article

Association between serum neurofilament light chain levels and grip strength among US adults: a cross-sectional study using National Health and Nutrition Examination Survey data from 2013 to 2014

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BMJ Open
Child Nutrition and Feeding Issues
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article

Association between serum neurofilament light chain levels and grip strength among US adults: a cross-sectional study using National Health and Nutrition Examination Survey data from 2013 to 2014

Kaisaierjiang Kadier, Abudureheman Zebibula, Weijie Zhang, Mulati Rexiati, Bingzhang Qiao, Diliyaer Dilixiati, Ying Yang, Daniyaer Nuerdebieke
article en
3 citations

Abstract

Our study demonstrates a strong, negative and linear correlation between elevated serum NfL levels and grip strength. Notably, our findings indicate that individuals aged between 60 and 75 years, those with physical inactivity and those with CKD exhibit a more pronounced reduction in grip strength with increasing serum NfL levels.

BMJ OpenVol. 15(4)
Xinjiang Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), First Affiliated Hospital of Xinjiang Medical University (CN), National Cancer Center (US)
Zero hunger
Openalex Percentile: Top 6%
Child Nutrition and Feeding Issues
4.41
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