Trajectories of Pontine Volume in Patients with Multiple System Atrophy
Pontine volume is a sensitive marker of disease progression, exhibiting a nonlinear decline with low intra-individual variability in measurements and greater volume loss in the earlier stages, reaching a pre-plateau phase in the later stages with advanced disability. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Hirohisa Watanabe (ORCID: https://orcid.org/0000-0001-8553-8536)
- Germain Arribarat (ORCID: https://orcid.org/0000-0002-8754-8110)
- Anne Pavy‐Le Traon (ORCID: https://orcid.org/0000-0002-9375-1553)
- Christoph Scherfler (ORCID: https://orcid.org/0000-0002-4885-5265)
- Mizuki Ito (ORCID: https://orcid.org/0000-0003-4470-1004)
- Mark Forrest Gordon (ORCID: https://orcid.org/0000-0002-0271-3050)
- Masahisa Katsuno (ORCID: https://orcid.org/0000-0001-9453-9311)
- Vincent Beliveau (ORCID: https://orcid.org/0000-0001-7805-279X)
- Alexandra Foubert‐Samier (ORCID: https://orcid.org/0000-0002-9811-2611)
- Olivier Rascol (ORCID: https://orcid.org/0000-0002-1410-6397)
- Florian Krismer (ORCID: https://orcid.org/0000-0002-4493-5073)
- Werner Poewe (ORCID: https://orcid.org/0000-0003-4367-0971)
- Patrice Péran (ORCID: https://orcid.org/0000-0001-7200-0139)
- Aya Ogura (ORCID: https://orcid.org/0000-0003-0928-8605)
- Margherita Fabbri (ORCID: https://orcid.org/0000-0001-7250-592X)
- Epifanio Bagarinao (ORCID: https://orcid.org/0000-0001-5000-6943)
- Kazuya Kawabata (ORCID: https://orcid.org/0000-0002-8851-4377)
- Klaus Seppi (ORCID: https://orcid.org/0000-0001-6503-1455)
- Wassilios G. Meissner (ORCID: https://orcid.org/0000-0003-2172-7527)
- Kazuhiro Hara (ORCID: https://orcid.org/0000-0001-8410-8550)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Innsbruck Medical University (AT)
- Fujita Health University (JP)
- Université de Bordeaux (FR)
- Inserm (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Institut des Maladies Neurodégénératives (FR)
- New Zealand Brain Research Institute (NZ)
- Bordeaux Population Health (FR)
- Fujita Health University Hospital (JP)
- Teva Pharmaceuticals (United States) (US)
- Institut des Maladies Métaboliques et Cardiovasculaires (FR)
- French Clinical Research Infrastructure Network (FR)
- Fujita Health University Bantane Hospital
- Nagoya University (JP)
- University of Otago (NZ)
- University of Applied Sciences Kufstein (AT)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1002/mds.30182
- Citations
- 4
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- Teva Pharmaceutical Industries
- Ministry of Health, Labour and Welfare
- H. Lundbeck A/S
- Allergan
- Avid Radiopharmaceuticals
- Japan Society for the Promotion of Science