Nuciferine Attenuates Cancer Cachexia‐Induced Muscle Wasting in Mice via HSP90AA1
Overall, we first discovered that NF retards CC-induced muscle atrophy by regulating AKT-mTOR and NF-κB signalling pathways through directly binding HSP90AA1, suggesting that NF may be an effective treatment for cancer cachexia.
Authors
- Abudumijiti Abulizi
- Bo Han (ORCID: https://orcid.org/0000-0002-6509-0313)
- Ji Liu (ORCID: https://orcid.org/0000-0002-9679-3716)
- Yulan Bai
- Baoxue Yang (ORCID: https://orcid.org/0000-0002-7966-2095)
- Awaguli Dawuti
- Lisha Ma (ORCID: https://orcid.org/0009-0006-3547-5315)
- Chaoyue Chen (ORCID: https://orcid.org/0000-0001-7536-2549)
- Ke‐Wu Zeng
- Xueyan An
Institutions
- Shihezi University (CN)
- Peking University (CN)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/jcsm.13777
- Citations
- 8
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.45
Funders
- National Natural Science Foundation of China