The Causal Relationship Between Opioid Use and Obstructive Sleep Apnea: A Bidirectional Mendelian Randomization Study
This study provides strong evidence of a unidirectional causal relationship in which opioid use increases the risk of developing OSA. These findings underscore the importance of monitoring patients who use opioids for potential respiratory complications, particularly OSA.
Authors
- Guoliang Shan
- Yanwu Jin (ORCID: https://orcid.org/0000-0002-8336-3872)
- Yufeng Ma
Institutions
- Second Hospital of Shandong University (CN)
Publication Details
- Journal
- Pain Physician
- Published
- 2025-03-26
- DOI
- https://doi.org/10.36076/ppj.2025.28.e147
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00