Characterizing the Influence of Relative Humidity and Ethanol Content on the Dynamic Size Distributions of Aerosols Generated from a Soft Mist Inhaler
The study highlights ethanol's role in optimizing particle size distribution, which is crucial for enhancing the therapeutic efficiency of inhaled medications. These results underscore the importance of tailoring formulation and environmental conditions to improve drug delivery outcomes in pulmonary therapies and the importance of recognising that aerosol particle size distributions are dynamic and highly compositionally dependent.
Authors
- Richard Henry Friend (ORCID: https://orcid.org/0000-0001-6565-6308)
- Jonathan P. Reid (ORCID: https://orcid.org/0000-0001-6022-1778)
- Jesús Sánchez Ruiz
- Yiliang Jiang (ORCID: https://orcid.org/0000-0002-2367-5997)
Institutions
- University of Bristol (GB)
- National Milk Records (United Kingdom) (GB)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1007/s11095-025-03851-1
- Primary Topic
- Inhalation and Respiratory Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Bristol
- Engineering and Physical Sciences Research Council