Mitochondrial Disorders After 12 Months of Human Immunodeficiency Virus Type 1 Preexposure Prophylaxis Based on Tenofovir Disoproxil Fumarate Plus Emtricitabine in Healthy Adults
TDF/FTC-based PrEP induces mitochondrial toxicity in healthy subjects after 12 months of treatment, negatively affecting mitochondrial function and morphology.
Authors
- Ana Serna‐Gallego (ORCID: https://orcid.org/0000-0002-7142-0315)
- Marta Herrero (ORCID: https://orcid.org/0000-0003-1090-9771)
- Luís F. López‐Cortés (ORCID: https://orcid.org/0000-0002-3804-3458)
- María Trujillo‐Rodríguez (ORCID: https://orcid.org/0000-0002-4716-4294)
- Marta Mejías-Trueba (ORCID: https://orcid.org/0000-0003-3819-4966)
- Esperanza Muñoz‐Muela (ORCID: https://orcid.org/0000-0002-5432-986X)
- Alicia Gutiérrez‐Valencia (ORCID: https://orcid.org/0000-0003-3445-1574)
- César Sotomayor (ORCID: https://orcid.org/0000-0002-9814-3389)
- Abraham Saborido-Alconchel
- Susana Fernández-Pérez
Institutions
- Universidad Loyola Andalucía (ES)
- Universidad Loyola (BO)
- Instituto de Biomedicina de Sevilla (ES)
- Primary Health Care (QA)
- Hospital Universitario Virgen del Rocío (ES)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-03-30
- DOI
- https://doi.org/10.1093/infdis/jiaf156
- Citations
- 4
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 9.01