Bioinformatics exploration of the S1PR1 receptor in various human cancers and its clinical relevance
S1PR1 plays a critical role in cancer progression through its expression, mutations, and modifications. These findings suggest that S1PR1 could be served as a potential biomarker and therapeutic target in cancer, but it need a further validation in clinical settings is warranted.
Authors
- Yu Huang (ORCID: https://orcid.org/0000-0001-7100-2546)
- Linghua Jia (ORCID: https://orcid.org/0000-0002-1908-641X)
- Zeng Li (ORCID: https://orcid.org/0000-0002-4501-4102)
- Xing Xiong
- Fanhui Zeng (ORCID: https://orcid.org/0000-0003-4333-5479)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1007/s12672-025-02241-8
- Citations
- 1
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.81