Novel silica-based polymer hemostatic matrix improves vessel patency rates in a coagulopathic porcine model with penetrating arterial injury
SBF and QCCG had comparable hemostatic efficacy and no difference in the number of applications, despite SBF packaging containing less material. There was no evidence of significant laboratory abnormalities at the study conclusion. Taken together, SBF may be an appropriate hemostatic agent for hemorrhagic injury and is able to maintain hemostasis following stressed movement. Its improved vessel patency suggests SBF may decrease tissue ischemia and improve limb salvage in vascular injuries.
Authors
- John A. Mares
- Matthew J. Bradley (ORCID: https://orcid.org/0000-0002-0375-3855)
- Justin Hutzler
- Alain Dagher (ORCID: https://orcid.org/0000-0002-0945-5779)
- Jason S. Radowsky (ORCID: https://orcid.org/0000-0002-0316-9907)
- Patrick F. Walker (ORCID: https://orcid.org/0000-0002-0871-2702)
- David M. Burmeister (ORCID: https://orcid.org/0000-0002-1256-0158)
- Lauren M Heyda
Institutions
- Henry M. Jackson Foundation (US)
- Bridge University (SS)
Publication Details
- Journal
- The Journal of Trauma: Injury, Infection, and Critical Care
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1097/ta.0000000000004596
- Primary Topic
- Hemostasis and retained surgical items
- Type
- article
- Field-Weighted Citation Impact
- 0.00