In Response to Comment on “Computed-Tomography-guided Percutaneous Bilateral Neurolytic Celiac Plexus Block with Alcohol for Upper Abdominal Visceral Cancer Pain”

First, I want to thank Dr. Ling Ye and his colleagues for reading my article and providing valuable feedback.In terms of the dexmedetomidine administration, the doses of dexmedetomidine added to long-acting local anesthetics ranged between a predetermined dose and a weight-based dose.As proven in previous studies, we use a predetermined dose (50 g) administered intravenously or perineurally as an adjuvant to local anesthetics (1,2).The study only included patients with ASA I or , excluding those with significant liver or renal dysfunction, heart failure, or severe arrhythmia.Then, while I agree that ropivacaine is safer than bupivacaine in terms of cardiac toxicity and adverse neurological manifestations, it is not available in my institute.Furthermore, a recent meta-analysis comparing the impact of adjuvants in ophthalmic regional anesthesia shows that our combination of lidocaine 2% and bupivacaine 0.5% was used in many trials (3).Lastly, the requirement for postoperative analgesia was the satisfaction-scoring criteria in our study.

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Publication Details

Journal
Pain Physician
Published
2025-03-26
DOI
https://doi.org/10.36076/ppj.2025.28.e229
Primary Topic
Pain Management and Opioid Use
Type
article
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article

In Response to Comment on “Computed-Tomography-guided Percutaneous Bilateral Neurolytic Celiac Plexus Block with Alcohol for Upper Abdominal Visceral Cancer Pain”

Huda F. Ghazaly
Pain Physician
Pain Management and Opioid Use
article

In Response to Comment on “Computed-Tomography-guided Percutaneous Bilateral Neurolytic Celiac Plexus Block with Alcohol for Upper Abdominal Visceral Cancer Pain”

Huda F. Ghazaly
article en

Abstract

First, I want to thank Dr. Ling Ye and his colleagues for reading my article and providing valuable feedback.In terms of the dexmedetomidine administration, the doses of dexmedetomidine added to long-acting local anesthetics ranged between a predetermined dose and a weight-based dose.As proven in previous studies, we use a predetermined dose (50 g) administered intravenously or perineurally as an adjuvant to local anesthetics (1,2).The study only included patients with ASA I or , excluding those with significant liver or renal dysfunction, heart failure, or severe arrhythmia.Then, while I agree that ropivacaine is safer than bupivacaine in terms of cardiac toxicity and adverse neurological manifestations, it is not available in my institute.Furthermore, a recent meta-analysis comparing the impact of adjuvants in ophthalmic regional anesthesia shows that our combination of lidocaine 2% and bupivacaine 0.5% was used in many trials (3).Lastly, the requirement for postoperative analgesia was the satisfaction-scoring criteria in our study.

Pain PhysicianVol. 28(2)
Aswan University (EG)
Good health and well-being
Openalex Percentile: Top 87%
Pain Management and Opioid Use
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