Plant ubiquitin E2 enzymes UBC32, UBC33, and UBC34 are involved in ERAD and function in host stress tolerance
Our findings establish UBC32, UBC33, and UBC34 as key components of the plant ERAD machinery, contributing to plant tolerance to both abiotic and biotic stress. Despite their close phylogenetic relationship, these E2 enzymes exhibit redundant, synergistic, or antagonistic roles depending on the specific stress response pathway, underscoring the complexity of their functional interactions.
Authors
- Lirong Zeng (ORCID: https://orcid.org/0000-0001-8802-4872)
- Bangjun Zhou (ORCID: https://orcid.org/0000-0003-2986-6310)
- Chaofeng Wang (ORCID: https://orcid.org/0000-0002-2768-5009)
- Yi Zhang (ORCID: https://orcid.org/0000-0003-0739-2185)
Institutions
- University of Nebraska–Lincoln (US)
- Chinese Academy of Sciences (CN)
- South China Botanical Garden (CN)
Publication Details
- Journal
- BMC Plant Biology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1186/s12870-025-06419-8
- Citations
- 5
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 5.76
Funders
- National Science Foundation
- U.S. Department of Agriculture
- University of Nebraska-Lincoln
- National Institute of Food and Agriculture