Brain Network Functional Connectivity in Children With a Concussion
Time after injury, age at injury, biological sex, and persistent symptom status are important moderators of FC after pediatric concussion for children seen in emergency department settings. Postacute FC may not enhance clinical diagnosis. Although within-network connectivity is preserved, between-network connectivity differences emerge after most children clinically recover and persist up to 6 months after pediatric concussion, providing a potential objective biomarker for lasting changes in brain function.
Authors
- Stephanie Deighton
- Miriam H. Beauchamp (ORCID: https://orcid.org/0000-0002-8637-6361)
- Emily L. Dennis (ORCID: https://orcid.org/0000-0001-7112-4009)
- Bradley G. Goodyear (ORCID: https://orcid.org/0000-0001-7289-7126)
- Nishard Abdeen (ORCID: https://orcid.org/0000-0002-6640-736X)
- Roger Zemek (ORCID: https://orcid.org/0000-0001-7807-2459)
- Kirk Graff (ORCID: https://orcid.org/0000-0001-7083-7904)
- Christian Beaulieu (ORCID: https://orcid.org/0000-0002-2342-3298)
- Adrian Onicas (ORCID: https://orcid.org/0000-0002-5953-8548)
- Signe Bray (ORCID: https://orcid.org/0000-0002-7626-2600)
- Bruce Björnson (ORCID: https://orcid.org/0000-0002-1465-6196)
- Catherine A. Lebel (ORCID: https://orcid.org/0000-0002-0344-4032)
- Mathieu Dehaes (ORCID: https://orcid.org/0000-0001-9852-6761)
- Ashley L. Ware (ORCID: https://orcid.org/0000-0002-8390-4915)
- Keith Owen Yeates (ORCID: https://orcid.org/0000-0001-7680-2892)
- William Craig (ORCID: https://orcid.org/0000-0002-4804-194X)
- Andrée‐Anne Ledoux (ORCID: https://orcid.org/0000-0002-3163-0844)
- Quynh Doan (ORCID: https://orcid.org/0000-0002-8435-7837)
- Jocelyn Gravel (ORCID: https://orcid.org/0000-0001-5901-4990)
- Stephen B. Freedman (ORCID: https://orcid.org/0000-0003-2319-6192)
- Sylvain Deschênes
Institutions
- University of British Columbia (CA)
- University of Ottawa (CA)
- University of Alberta (CA)
- University of Calgary (CA)
- Georgia State University (US)
- Washington University in St. Louis (US)
- University of Utah (US)
- Children's Hospital of Eastern Ontario (CA)
- Alberta Children's Hospital (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Glenrose Rehabilitation Hospital (CA)
- BC Children's Hospital (CA)
- Stollery Children's Hospital (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1212/wnl.0000000000213502
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.86