A Regional Mapping of Articular Cartilage Integrity and Biphasic Properties in Healthy and Osteoarthritic Trapeziometacarpal Joints
A regional pattern in articular cartilage degeneration, including changes in biphasic properties evidenced by an increased equilibrium modulus, during TMC OA progression is evident with the most significant changes occurring in the volar ulnar region of the metacarpal and volar central and volar ulnar regions of the trapezium. These changes in articular cartilage can be correlated to an attenuated VLC.
Authors
- Hai Yao (ORCID: https://orcid.org/0000-0001-5130-5128)
- Shangping Wang (ORCID: https://orcid.org/0000-0003-0049-2212)
- Dane Daley (ORCID: https://orcid.org/0000-0002-9620-1311)
- Nathan Buchweitz
- Lizzie Walker (ORCID: https://orcid.org/0009-0001-9980-6260)
- Huijun Li (ORCID: https://orcid.org/0000-0002-2896-3867)
- Yongren Wu (ORCID: https://orcid.org/0000-0002-5411-8528)
- Daniel Gordon
Institutions
- Medical University of South Carolina (US)
- Clemson University (US)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1007/s10439-025-03726-x
- Citations
- 2
- Primary Topic
- Orthopedic Surgery and Rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Clemson University
- Wake Forest University
- National Institutes of Health
- National Institute of General Medical Sciences