Assessment of antiseizure medication adherence based on postmortem toxicology and claimed prescriptions in cases of sudden unexpected death in epilepsy
By uniquely matching register-based prescription data with postmortem toxicology findings, we ascertained that 73% of SUDEP cases adhered to their claimed ASM, underscoring the necessity for continued vigilance in seizure management. However, improving medication adherence may possess preventive potential for SUDEP, as 22% exhibited nonadherence to their claimed ASM.
Authors
- Marius Kløvgaard (ORCID: https://orcid.org/0000-0003-0447-2841)
- Carl Johann Hansen (ORCID: https://orcid.org/0000-0003-4541-6248)
- Jytte Banner (ORCID: https://orcid.org/0000-0002-7559-1285)
- Marie Kroman Palsøe (ORCID: https://orcid.org/0009-0006-7598-4974)
- Kristían Línnet (ORCID: https://orcid.org/0000-0001-6974-5535)
- Christian Tobias Torp-Pedersen (ORCID: https://orcid.org/0000-0003-2892-6131)
- Jacob Tfelt‐Hansen (ORCID: https://orcid.org/0000-0003-3895-9316)
Institutions
- University of Copenhagen (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Zealand University Hospital (DK)
- Nordsjællands Hospital (DK)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1111/epi.18354
- Citations
- 2
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Novo Nordisk
- Faculty of Health and Medical Sciences, University of Western Australia
- Det Sundhedsvidenskabelige Fakultet, Københavns Universitet