Volumetric Measures of Capillary Nonperfusion on Optical Coherence Tomography Angiography Detect Early Ischemia in Diabetes Without Retinopathy
Using a stringent threshold (20 µm), volumetric OCTA imaging detects significant DCP perfusion defects in diabetic eyes even before DR onset, whereas traditional 2D OCTA does not. Volumetric scans may therefore be more sensitive to early ischemia in diabetes.
Authors
- Daniela Castellanos‐Canales
- Hisashi Fukuyama (ORCID: https://orcid.org/0000-0002-5991-3846)
- Nicole L. Decker (ORCID: https://orcid.org/0009-0009-9777-5702)
- Janice X. Ong (ORCID: https://orcid.org/0000-0001-8018-8290)
- H. Lee
- Amani A. Fawzi (ORCID: https://orcid.org/0000-0002-9568-3558)
Institutions
- Northwestern University (US)
- Hyogo Medical University (JP)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1167/iovs.66.4.2
- Citations
- 4
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.83
Funders
- National Institutes of Health
- Genentech