Herpes Zoster Occurring After Injection of Botulinum Toxin and Hyaluronic Acid

Botulinum toxin, as a common facial wrinkle removal product, can be used for facial rejuvenation or improvement of skin texture, which is a commonly used cosmetic injectable product. However, botulinum toxin may lead to decreased immune function, causing a series of subsequent complications. This case report describes a 32-year-old female patient who developed herpes zoster after receiving injections of semaglutide, botulinum toxin, and hyaluronic acid. Viral infection and decreased immune function are common triggers of herpes zoster. After injection of botulinum toxin, the local immune response may be affected, which may activate the latent varicella-zoster virus or lead to decreased immune function that causes herpes zoster.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2025-04-01
DOI
https://doi.org/10.1097/scs.0000000000011239
Primary Topic
Herpesvirus Infections and Treatments
Type
article
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article

Herpes Zoster Occurring After Injection of Botulinum Toxin and Hyaluronic Acid

Jintian Hu, Ziming Zhang, Xueshang Su, Jun Zhuang et al.
Journal of Craniofacial Surgery
Herpesvirus Infections and Treatments
article

Herpes Zoster Occurring After Injection of Botulinum Toxin and Hyaluronic Acid

Jintian Hu, Ziming Zhang, Xueshang Su, Jun Zhuang, Yutong Liang, G. Tan, Rui-Ning Ouyang
article en

Abstract

Botulinum toxin, as a common facial wrinkle removal product, can be used for facial rejuvenation or improvement of skin texture, which is a commonly used cosmetic injectable product. However, botulinum toxin may lead to decreased immune function, causing a series of subsequent complications. This case report describes a 32-year-old female patient who developed herpes zoster after receiving injections of semaglutide, botulinum toxin, and hyaluronic acid. Viral infection and decreased immune function are common triggers of herpes zoster. After injection of botulinum toxin, the local immune response may be affected, which may activate the latent varicella-zoster virus or lead to decreased immune function that causes herpes zoster.

Journal of Craniofacial SurgeryVol. 36(6)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Southern Medical University (CN)
Openalex Percentile: Top 90%
Herpesvirus Infections and Treatments
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Herpes Zoster Occurring After Injection of Botulinum Toxin and Hyaluronic Acid — Jintian Hu, Ziming Zhang, et al. · Journal of Craniofacial Surgery (2025) | TGRS Research Map | TGRS