Ablative Fractional Lasers Versus Needle-Based Devices for Poly-l-Lactic Acid Delivery: An Optical Coherence Tomography and Histology Study
Ablative fractional lasers effectively delivered PLLA through the skin, while needle-based devices showed minimal uptake. Among AFLs, channel geometry influenced vertical particle distribution. In vivo and clinical studies are needed to assess PLLA retention and its impact on remodeling.
Authors
- Ga Ram Ahn (ORCID: https://orcid.org/0000-0002-5696-4699)
- Hye Jin Chung (ORCID: https://orcid.org/0000-0003-0204-4085)
- Nelson Ugwu (ORCID: https://orcid.org/0000-0002-8647-5300)
- Parita T. Suwan (ORCID: https://orcid.org/0009-0007-5612-4044)
- Dieter Manstein (ORCID: https://orcid.org/0000-0002-4508-045X)
Institutions
- Beth Israel Deaconess Medical Center (US)
- Massachusetts General Hospital (US)
- Harvard Affiliated Emergency Medicine Residency (US)
Publication Details
- Journal
- Dermatologic Surgery
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1097/dss.0000000000004631
- Citations
- 1
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 2.00