Assisted Reproduction Technology Treatment Outcomes in Female Carriers of 21-Hydroxylase Deficiency
Female patients who carry a pathogenic CYP21A2 variant achieve in vitro fertilization outcomes comparable to noncarriers. These findings support maintaining standard assisted reproductive treatment protocols for carriers and help provide personalized counseling for carriers identified through genetic screening.
Authors
- Carlos Hernández-Nieto (ORCID: https://orcid.org/0000-0002-6703-1341)
- Joseph A. Lee (ORCID: https://orcid.org/0000-0002-2739-2695)
- Alan B. Copperman
- Tanmoy Mukherjee (ORCID: https://orcid.org/0000-0001-5571-5896)
- Arthur Arcaz (ORCID: https://orcid.org/0000-0002-4425-0576)
- Teresa A. Cacchione
Institutions
- Reproductive Medicine Associates of New York (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1210/clinem/dgaf198
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00