Application of Semiconductor Biochips in Disease Monitoring

With an increasing awareness of health and the rapid development of biotechnology, semiconductor biochips, as an important tool at the intersection of integrated circuits and biomedical fields, have shown great potential in disease monitoring and other areas. This paper analyzes the working principles of semiconductor biochips and their specific applications in disease detection, exploring how they achieve early disease diagnosis by monitoring changes in biomarkers such as ion concentration and metabolic products. Through literature review and case analysis, this study summarizes the current mainstream types of biochips (such as microfluidic chips and electrochemical sensor chips) and their effectiveness in monitoring diseases like cancer and diabetes. The results indicate that semiconductor biochips offer advantages such as high sensitivity, rapid response, and low cost, but they still face challenges in biocompatibility and large-scale production. In the future, with advancements in materials science and nanotechnology, biochips are expected to play a more significant role in personalized medicine and point-of-care testing (POCT).

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Publication Details

Journal
Applied and Computational Engineering
Published
2025-04-03
DOI
https://doi.org/10.54254/2755-2721/2025.21798
Primary Topic
Advanced Biosensing Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Application of Semiconductor Biochips in Disease Monitoring

Zetian Fu
Applied and Computational Engineering
Advanced Biosensing Techniques and Applications
article

Application of Semiconductor Biochips in Disease Monitoring

Zetian Fu
article en

Abstract

With an increasing awareness of health and the rapid development of biotechnology, semiconductor biochips, as an important tool at the intersection of integrated circuits and biomedical fields, have shown great potential in disease monitoring and other areas. This paper analyzes the working principles of semiconductor biochips and their specific applications in disease detection, exploring how they achieve early disease diagnosis by monitoring changes in biomarkers such as ion concentration and metabolic products. Through literature review and case analysis, this study summarizes the current mainstream types of biochips (such as microfluidic chips and electrochemical sensor chips) and their effectiveness in monitoring diseases like cancer and diabetes. The results indicate that semiconductor biochips offer advantages such as high sensitivity, rapid response, and low cost, but they still face challenges in biocompatibility and large-scale production. In the future, with advancements in materials science and nanotechnology, biochips are expected to play a more significant role in personalized medicine and point-of-care testing (POCT).

Applied and Computational EngineeringVol. 140(1)
UNSW Sydney (AU)
Openalex Percentile: Top 94%
Advanced Biosensing Techniques and Applications
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Application of Semiconductor Biochips in Disease Monitoring — Zetian Fu · Applied and Computational Engineering (2025) | TGRS Research Map | TGRS