Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS)

Although half of the respondents reported experiencing side effects, 39.0% of past users identified side effects as a reason for discontinuation. This suggests a gap between patient experience and perceived reasons for discontinuation. A notable finding from the study is the significant role of healthcare providers in influencing the decisions to start or stop sMRA treatment. Therefore, future research should focus on exploring the factors that shape healthcare providers' decision-making processes when initiating and discontinuing treatment options.

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Publication Details

Journal
Pragmatic and Observational Research
Published
2025-04-01
DOI
https://doi.org/10.2147/por.s489802
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00
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article

Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS)

Alain Gay, Vincent J. Willey, Judith J. Stephenson, Elena Pessina et al.
Pragmatic and Observational Research
Hormonal Regulation and Hypertension
article

Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS)

Alain Gay, Vincent J. Willey, Judith J. Stephenson, Elena Pessina, Charlie Scott, Nihar R. Desai, Nikolaus G. Oberprieler, Kerstin Folkerts, Rakesh K. Singh, Emma Richard, Chia‐Chen Teng
article en

Abstract

Although half of the respondents reported experiencing side effects, 39.0% of past users identified side effects as a reason for discontinuation. This suggests a gap between patient experience and perceived reasons for discontinuation. A notable finding from the study is the significant role of healthcare providers in influencing the decisions to start or stop sMRA treatment. Therefore, future research should focus on exploring the factors that shape healthcare providers' decision-making processes when initiating and discontinuing treatment options.

Pragmatic and Observational ResearchVol. Volume 16
Clarion University (US), Bayer (Norway) (NO), Eli Lilly (United States) (US), Yale University (US), EP Analytics (United States) (US), Bayer (Italy) (IT), Health Economics and Outcomes Research (United Kingdom) (GB), Bayer (Germany) (DE)
Zero hunger
Openalex Percentile: Top 91%
Hormonal Regulation and Hypertension
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Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS) — Alain Gay, Vincent J. Willey, et al. · Pragmatic and Observational Research (2025) | TGRS Research Map | TGRS