Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging
The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragonhead (<em>Dracocephalum moldavica</em> L.), a natural plant-based compound. <em>In vitro</em> studies have shown that the extract stimulates genes crucial for skin structure. Further, a double-masked, randomized, placebo-controlled clinical trial in female volunteers demonstrated that oral supplementation with the extract significantly improves skin hydration and increases dermal and full-skin thickness. These findings suggest that the Moldavian dragonhead extract is a promising natural alternative to traditional interventions, offering a holistic approach to improve the skin's dermal network and combat skin aging.
Authors
- Franziska Wandrey (ORCID: https://orcid.org/0000-0002-1296-4021)
- Julia Baumann (ORCID: https://orcid.org/0000-0001-5224-2093)
- Torsten Grothe (ORCID: https://orcid.org/0000-0003-3298-4924)
- Eva Bönzli
Institutions
- Interstate University of Applied Sciences of Technology Buchs (CH)
Publication Details
- Journal
- OBM Geriatrics
- Published
- 2025-04-03
- DOI
- https://doi.org/10.21926/obm.geriatr.2502305
- Citations
- 4
- Primary Topic
- Collagen: Extraction and Characterization
- Type
- article
- Field-Weighted Citation Impact
- 2.39