Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging

The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragonhead (<em>Dracocephalum moldavica</em> L.), a natural plant-based compound. <em>In vitro</em> studies have shown that the extract stimulates genes crucial for skin structure. Further, a double-masked, randomized, placebo-controlled clinical trial in female volunteers demonstrated that oral supplementation with the extract significantly improves skin hydration and increases dermal and full-skin thickness. These findings suggest that the Moldavian dragonhead extract is a promising natural alternative to traditional interventions, offering a holistic approach to improve the skin's dermal network and combat skin aging.

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Publication Details

Journal
OBM Geriatrics
Published
2025-04-03
DOI
https://doi.org/10.21926/obm.geriatr.2502305
Citations
4
Primary Topic
Collagen: Extraction and Characterization
Type
article
Field-Weighted Citation Impact
2.39
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article

Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging

Franziska Wandrey, Julia Baumann, Torsten Grothe, Eva Bönzli
4 citations
OBM Geriatrics
Collagen: Extraction and Characterization
2.39
article

Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging

Franziska Wandrey, Julia Baumann, Torsten Grothe, Eva Bönzli
article en
4 citations

Abstract

The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragonhead (<em>Dracocephalum moldavica</em> L.), a natural plant-based compound. <em>In vitro</em> studies have shown that the extract stimulates genes crucial for skin structure. Further, a double-masked, randomized, placebo-controlled clinical trial in female volunteers demonstrated that oral supplementation with the extract significantly improves skin hydration and increases dermal and full-skin thickness. These findings suggest that the Moldavian dragonhead extract is a promising natural alternative to traditional interventions, offering a holistic approach to improve the skin's dermal network and combat skin aging.

OBM GeriatricsVol. 09(02)
Interstate University of Applied Sciences of Technology Buchs (CH)
Openalex Percentile: Top 13%
Collagen: Extraction and Characterization
2.39
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Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging — Franziska Wandrey, Julia Baumann, et al. · OBM Geriatrics (2025) | TGRS Research Map | TGRS