Comparison of malignant melanoma development in people living with HIV/AIDS

Densely pigmented hyphae in the nail plate.Hematoxylin and eosin staining, 40x.Dermoscopy of the nail plate revealing area of irregular, asymmetric pigmentation with multiple colors.Conclusions: Although Tinea Nigra is more frequent in tropical regions, it is crucial to expand awareness of this mycosis, its clinical presentation, and its differential diagnoses.The rarity of reports on the mimicry of acral melanoma by Tinea Nigra underscores the relevance of this study, given the potential severity of a misdiagnosis.Such errors could lead to unnecessary surgical interventions and significant psychological distress for patients.In the presented case, the patient's advanced age, subungual lesion, and dermoscopic findings-characterized by irregular pigmentation, asymmetry, and multiple colors-compounded the diagnostic challenge.This case highlights the need to include Tinea Nigra in the differential diagnosis of acral pigmented lesions and underscores the critical role of expert pathologists in slide analysis to prevent false diagnoses of acral melanoma.

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Publication Details

Journal
EJC Skin Cancer
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ejcskn.2025.100440
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
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article

Comparison of malignant melanoma development in people living with HIV/AIDS

Maria Krotewicz
EJC Skin Cancer
Cutaneous Melanoma Detection and Management
article

Comparison of malignant melanoma development in people living with HIV/AIDS

Maria Krotewicz
article en

Abstract

Densely pigmented hyphae in the nail plate.Hematoxylin and eosin staining, 40x.Dermoscopy of the nail plate revealing area of irregular, asymmetric pigmentation with multiple colors.Conclusions: Although Tinea Nigra is more frequent in tropical regions, it is crucial to expand awareness of this mycosis, its clinical presentation, and its differential diagnoses.The rarity of reports on the mimicry of acral melanoma by Tinea Nigra underscores the relevance of this study, given the potential severity of a misdiagnosis.Such errors could lead to unnecessary surgical interventions and significant psychological distress for patients.In the presented case, the patient's advanced age, subungual lesion, and dermoscopic findings-characterized by irregular pigmentation, asymmetry, and multiple colors-compounded the diagnostic challenge.This case highlights the need to include Tinea Nigra in the differential diagnosis of acral pigmented lesions and underscores the critical role of expert pathologists in slide analysis to prevent false diagnoses of acral melanoma.

EJC Skin CancerVol. 3
National Institute of Oncology (HU), The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
Good health and well-being
Openalex Percentile: Top 90%
Cutaneous Melanoma Detection and Management
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Comparison of malignant melanoma development in people living with HIV/AIDS — Maria Krotewicz · EJC Skin Cancer (2025) | TGRS Research Map | TGRS