Rapid response of genital locally advanced Basal Cell Carcinoma with reduced schedule Sonidegib

Background: Basal Cell Carcinoma (BCC) represents a common neoplasm affecting sun-exposed sites, while it rarely arises in genital areas. The surgical excision with adequate margins is the preferred option for the curative treatment of BCC, despite it is difficultly obtained in the locally advanced lesions (laBCCs). To date, only sporadic cases of genital laBCC have been treated with Hedgehog Pathway inhibitors (HPi).

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Publication Details

Journal
EJC Skin Cancer
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ejcskn.2025.100319
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
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article

Rapid response of genital locally advanced Basal Cell Carcinoma with reduced schedule Sonidegib

Elisa Zavattaro, Pamela Farinelli, Paola Savoia, Giulio Giorgione et al.
EJC Skin Cancer
Nonmelanoma Skin Cancer Studies
article

Rapid response of genital locally advanced Basal Cell Carcinoma with reduced schedule Sonidegib

Elisa Zavattaro, Pamela Farinelli, Paola Savoia, Giulio Giorgione, Vanessa Tarantino, B. Nadiani
article en

Abstract

Background: Basal Cell Carcinoma (BCC) represents a common neoplasm affecting sun-exposed sites, while it rarely arises in genital areas. The surgical excision with adequate margins is the preferred option for the curative treatment of BCC, despite it is difficultly obtained in the locally advanced lesions (laBCCs). To date, only sporadic cases of genital laBCC have been treated with Hedgehog Pathway inhibitors (HPi).

EJC Skin CancerVol. 3
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT), Azienda Ospedaliero Universitaria Maggiore della Carita (IT), Azienda Ospedaliera Ospedale Maggiore (IT), Piedmont University (US)
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Nonmelanoma Skin Cancer Studies
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