Characteristics and immunoprotective functions of three cysteine proteases from Clonorchis sinensis
These findings suggest that CsCP1-3 elicit robust antibody and cellular immune responses, mitigating liver damage caused by <i>C. sinensis</i> infection. CsCP1, in particular, induces a potent mixed Th1/Th2 response, positioning it as a promising vaccine candidate.
Authors
- Kai Liang
- Lili Tang (ORCID: https://orcid.org/0000-0002-6179-8920)
- Yaoting Li (ORCID: https://orcid.org/0000-0003-2023-4085)
- Ting‐Jang Lu (ORCID: https://orcid.org/0000-0002-3956-8272)
- Shuai Wei (ORCID: https://orcid.org/0000-0002-0819-7157)
- Yu Chen (ORCID: https://orcid.org/0000-0002-1235-4645)
- Yanwen Li
- Shanshan He (ORCID: https://orcid.org/0000-0002-6007-9975)
- Dengyu Liu (ORCID: https://orcid.org/0000-0002-8245-9573)
- Xiaoqin Li
- Yunliang Shi
- Yan-Ting Lai
Institutions
- Guangxi Medical University (CN)
- Longgang Central Hospital (CN)
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Taiwan Centers for Disease Control (TW)
- Hechi University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1550775
- Citations
- 1
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region