Strength and Durability of Respiratory Syncytial Virus Prefusion F Immunoglobulin G Following Infection and Exposure in a Household Cohort, 2014–2022
Pre-F IgG is a reliable correlate of protection for RSV infection risk. We found that RSV pre-F IgG-mediated protection starts to wane 6 months after infection. Therefore, scheduling of RSV vaccination should be evaluated so that individuals with the highest risk of severe disease are protected throughout the RSV season.
Authors
- Arnold S. Monto (ORCID: https://orcid.org/0000-0003-3018-435X)
- Emily Toth Martin (ORCID: https://orcid.org/0000-0002-5771-8895)
- Matthew Smith
- Yangyupei Yang (ORCID: https://orcid.org/0000-0002-6011-4152)
- Adam S. Lauring (ORCID: https://orcid.org/0000-0003-2906-8335)
- Amy P. Callear (ORCID: https://orcid.org/0009-0009-6663-2784)
- Kalee E. Rumfelt (ORCID: https://orcid.org/0000-0001-5128-0274)
- Casey Juntila
Institutions
- University of Michigan (US)
- Michigan Medicine (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1093/infdis/jiaf168
- Citations
- 4
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 5.42
Funders
- National Institutes of Health
- Centers for Disease Control and Prevention