Putative Mechanisms of Electroconvulsive Therapy in Treatment-Resistant Schizophrenia Examined Using Magnetic Resonance Imaging
ECT may drive clinical improvement in refractory schizophrenia by increasing amygdala volumes and reducing posterior cerebellar connectivity. Randomized sham-controlled trials can confirm these findings in the future.
Authors
- Matcheri S. Keshavan (ORCID: https://orcid.org/0000-0002-5945-888X)
- Neelabja Roy (ORCID: https://orcid.org/0000-0001-7016-9256)
- Rose Dawn Bharath (ORCID: https://orcid.org/0000-0002-7464-4250)
- Urvakhsh Meherwan Mehta (ORCID: https://orcid.org/0000-0002-2252-9189)
- Jagadisha Thirthalli (ORCID: https://orcid.org/0000-0003-3998-9672)
- Dhruva Ithal (ORCID: https://orcid.org/0000-0001-7689-8978)
- Rakshathi Basavaraju (ORCID: https://orcid.org/0000-0001-7026-0818)
- Nicolas R. Bolo (ORCID: https://orcid.org/0000-0002-9941-622X)
- Bangalore N. Gangadhar (ORCID: https://orcid.org/0000-0002-9887-6515)
Institutions
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Massachusetts Mental Health Center (US)
- National Institute of Mental Health and Neurosciences (IN)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1016/j.bpsgos.2025.100494
- Citations
- 3
- Primary Topic
- Electroconvulsive Therapy Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Wellcome Trust
- Department of Biotechnology, Ministry of Science and Technology, India
- The Wellcome Trust DBT India Alliance