Metagenomic analysis reveals the diversity of the vaginal virome and its association with vaginitis
These findings provide new insights into the composition and structure of the vaginal virome and its potential association with vaginal dysbiosis. The distinct virome characteristics observed in women with vaginitis highlight the relevance of viral communities in reproductive health. Future studies incorporating individual-level sequencing and metatranscriptomics are warranted to explore intra-host viral dynamics, assess viral activity, and clarify the functional roles of vaginal viruses in host-microbiome interactions.
Authors
- Qiang Lu (ORCID: https://orcid.org/0000-0001-7241-5131)
- Zhipeng Wang (ORCID: https://orcid.org/0009-0008-4211-5662)
- Ziyuan Dai (ORCID: https://orcid.org/0000-0002-3560-6091)
- Wen Zhang (ORCID: https://orcid.org/0000-0001-8413-0598)
- Hongmei Chen (ORCID: https://orcid.org/0000-0002-5621-4978)
- Jun Chen (ORCID: https://orcid.org/0000-0002-3439-0495)
- Lingzhi Zhang
- Mingzhong Sun (ORCID: https://orcid.org/0000-0001-9001-4796)
- Z. W. Ge
- Rong Zhu
- Xiaojü Lu (ORCID: https://orcid.org/0000-0002-2216-5004)
Institutions
- Jiangsu University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-04-03
- DOI
- https://doi.org/10.3389/fcimb.2025.1582553
- Citations
- 5
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 5.92
Funders
- Nantong University