Missing a trick? Bupropion for the pharmacological treatment of depression in the UK
Bupropion is not licensed as an antidepressant in the UK, limiting its use. We highlight bupropion's distinct pharmacological profile and its potential benefits in treatment-resistant depression and people experiencing selective serotonin reuptake inhibitor-induced sexual dysfunction. The National Health Service repurposing medicines programme could improve equity of access for UK patients.
Authors
- Philip J. Cowen (ORCID: https://orcid.org/0000-0001-5518-6138)
- Michael Browning (ORCID: https://orcid.org/0000-0001-9108-3144)
Institutions
- Oxford Health NHS Foundation Trust (GB)
- University of Oxford (GB)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1192/bjp.2025.50
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00