Comparative study of the effects of prenatal sevoflurane exposure at different cortical stages on forebrain development and maturation in offspring
Our results indicate that PSE at E12.5 and E18.5 leads to abnormalities in the migration of glutamatergic and GABAergic neurons, affecting long-term anxiety-like behaviors and causing learning and memory impairments in offspring mice.
Authors
- Huandi Weng
- Yalan Li (ORCID: https://orcid.org/0000-0002-3495-4721)
- Tianyuan Wang (ORCID: https://orcid.org/0000-0002-3970-0771)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Ningxia Medical University (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-04-03
- DOI
- https://doi.org/10.3389/fnins.2025.1556703
- Citations
- 1
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- National Natural Science Foundation of China
- Ningxia Medical University
- Natural Science Foundation of Ningxia Province
- Key Research and Development Program of Ningxia
- Research and Development