Cu-catalyzed borylative cyclization of <i>N</i>-(<i>o</i>-alkynylaryl)imines
We report herein the first copper-catalyzed intramolecular borylative cyclization of alkynes with imines, providing efficient access to alkenyl boronate-containing indolines. Preliminary mechanistic studies suggested a nucleophilic addition process for the alkenyl copper-trapping step, in which the nucleophilicity of alkenyl copper was largely enhanced by the formation of boronate complexes.
Authors
- Jianzhou Gui (ORCID: https://orcid.org/0000-0002-8406-9886)
- Hongping Zhao (ORCID: https://orcid.org/0000-0002-5169-5290)
- Tingting Zhang (ORCID: https://orcid.org/0000-0002-8227-3728)
- Liu Y (ORCID: https://orcid.org/0000-0003-2030-643X)
- Mo Yu (ORCID: https://orcid.org/0000-0003-0949-6113)
- Cheng‐Yu He (ORCID: https://orcid.org/0000-0003-3426-279X)
- Yu-Chuan Pu
Institutions
- China West Normal University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00679a
- Citations
- 1
- Primary Topic
- Organoboron and organosilicon chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.94