Easy access to a self-assembled glycolipid derived from bhilawanol: a promising anti-cancer drug

In this study, we synthesised a series of self-assembling glycoconjugates derived from bhilawanol under environmentally friendly conditions in good yields. These self-assembling glycoconjugates displayed anti-cancer activity toward HeLa cells at an IC<sub>50</sub> value of 125 μM with minimal side effects, holding immense potential in cancer therapeutics.

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Publication Details

Journal
Chemical Communications
Published
2025-01-01
DOI
https://doi.org/10.1039/d5cc01621e
Citations
1
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
0.81

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article

Easy access to a self-assembled glycolipid derived from bhilawanol: a promising anti-cancer drug

Kajal Sandhu, Subbiah Nagarajan, Tohira Banoo, S Chockalingam
1 citations
Chemical Communications
RNA Interference and Gene Delivery
0.81
article

Easy access to a self-assembled glycolipid derived from bhilawanol: a promising anti-cancer drug

Kajal Sandhu, Subbiah Nagarajan, Tohira Banoo, S Chockalingam
article en
1 citations

Abstract

In this study, we synthesised a series of self-assembling glycoconjugates derived from bhilawanol under environmentally friendly conditions in good yields. These self-assembling glycoconjugates displayed anti-cancer activity toward HeLa cells at an IC<sub>50</sub> value of 125 μM with minimal side effects, holding immense potential in cancer therapeutics.

Chemical CommunicationsVol. 61(37)
National Institute of Technology Warangal (IN)
National Institute of Technology Warangal, Department of Science and Technology, Ministry of Science and Technology, India, Science and Engineering Research Board
Openalex Percentile: Top 30%
RNA Interference and Gene Delivery
0.81
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