Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report

Lung squamous cell carcinoma (SCC) is a subtype of non-small cell lung cancer with high incidence and mortality rates. While chemotherapy and immune checkpoint inhibitors (ICIs) have become crucial treatment options for SCC, these may be associated with unforeseen complications. Here, we present a 65-year-old male of hemoptysis caused by a pulmonary artery pseudoaneurysm (PAP) after chemotherapy combined with tislelizumab for lung SCC. After confirmation with angiography, successful embolization was performed to occlude the pseudoaneurysm and proximal artery. To our knowledge, this is the first reported case of PAP formation after chemotherapy combined with tislelizumab for lung SCC.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-04-03
DOI
https://doi.org/10.3389/fmed.2025.1524248
Citations
2
Primary Topic
Vascular Anomalies and Treatments
Type
article
Field-Weighted Citation Impact
3.25
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article

Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report

Yongjuan Wu, Jing-Zhong Wang, Xiaoqi Li, Yulong Zheng et al.
2 citations
Frontiers in Medicine
Vascular Anomalies and Treatments
3.25
article

Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report

Yongjuan Wu, Jing-Zhong Wang, Xiaoqi Li, Yulong Zheng, Xuejiao Yang
article en
2 citations

Abstract

Lung squamous cell carcinoma (SCC) is a subtype of non-small cell lung cancer with high incidence and mortality rates. While chemotherapy and immune checkpoint inhibitors (ICIs) have become crucial treatment options for SCC, these may be associated with unforeseen complications. Here, we present a 65-year-old male of hemoptysis caused by a pulmonary artery pseudoaneurysm (PAP) after chemotherapy combined with tislelizumab for lung SCC. After confirmation with angiography, successful embolization was performed to occlude the pseudoaneurysm and proximal artery. To our knowledge, this is the first reported case of PAP formation after chemotherapy combined with tislelizumab for lung SCC.

Frontiers in MedicineVol. 12
Hubei University of Arts and Science (CN), Xiangyang Central Hospital (CN)
Good health and well-being
Openalex Percentile: Top 9%
Vascular Anomalies and Treatments
3.25
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Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report — Yongjuan Wu, Jing-Zhong Wang, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS