Total and Free Placental Growth Factor Levels During Preeclampsia and Fetal Growth Restriction

Placental dysfunction associated with preeclampsia, characterized by reduced free PlGF levels but unchanged total PlGF, is driven by excessive placental production of sFLT1. Placental dysfunction associated with SGA, marked by reductions in both free and total PlGF, is mediated by decreased placental PlGF production.

Authors

D. Redel (ORCID: https://orcid.org/0000-0003-0821-0910)
H. Abbas
S. Ananth Karumanchi (ORCID: https://orcid.org/0000-0002-2281-6831)
Édouard Lecarpentier (ORCID: https://orcid.org/0000-0002-1290-2939)
Audrey Ridoux
A. Jungelson
B. Haddad (ORCID: https://orcid.org/0009-0001-0601-7810)
M. Barthe

Institutions

Cedars-Sinai Medical Center (US)
Centre National de la Recherche Scientifique (FR)
Inserm (FR)
Université Paris-Est Créteil (FR)
Paris-Est Sup (FR)
Institut Cochin (FR)
Clinique Ambroise Paré (FR)
Hôpital Intercommunal de Créteil (FR)

Publication Details

Journal: Hypertension
Published: 2025-04-02
DOI: https://doi.org/10.1161/hypertensionaha.125.24736
Citations: 4
Primary Topic: Pregnancy and preeclampsia studies
Type: article
Field-Weighted Citation Impact: 8.23

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article

Total and Free Placental Growth Factor Levels During Preeclampsia and Fetal Growth Restriction

D. Redel, H. Abbas, S. Ananth Karumanchi, Édouard Lecarpentier et al.

Apr 2, 2025

4 citations

Hypertension

Pregnancy and preeclampsia studies

8.23

article

Total and Free Placental Growth Factor Levels During Preeclampsia and Fetal Growth Restriction

D. Redel, H. Abbas, S. Ananth Karumanchi, Édouard Lecarpentier, Audrey Ridoux, A. Jungelson, B. Haddad, M. Barthe

April 2, 2025article en

4 citations

Abstract

Placental dysfunction associated with preeclampsia, characterized by reduced free PlGF levels but unchanged total PlGF, is driven by excessive placental production of sFLT1. Placental dysfunction associated with SGA, marked by reductions in both free and total PlGF, is mediated by decreased placental PlGF production.

HypertensionVol. 82(5)

Cedars-Sinai Medical Center (US), Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris-Est Créteil (FR), Paris-Est Sup (FR), Institut Cochin (FR), Clinique Ambroise Paré (FR), Hôpital Intercommunal de Créteil (FR)

Good health and well-being

Openalex Percentile: Top 3%

Pregnancy and preeclampsia studies

8.23

DOI Source OpenAlex

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Total and Free Placental Growth Factor Levels During Preeclampsia and Fetal Growth Restriction — D. Redel, H. Abbas, et al. · Hypertension (2025) | TGRS Research Map | TGRS