Visible light-promoted cascade synthesis of pyrazolidinones <i>via N</i>-aryl glycine and azomethine imines

We present an effective, visible light-driven method for the synthesis of <i>N</i>-(β-amino)pyrazolidin-3-ones from <i>N</i>-aryl glycine and azomethine imines. This additive-free protocol utilizes blue light (<i>λ</i>_max = 435-445 nm) at room temperature, enabling a radical-mediated cascade reaction that delivers a diverse range of pyrazolidinones in yields up to 99%. The mild conditions, high efficiency, and broad substrate scope of this process make it an attractive strategy for streamlined synthesis in drug discovery and material science.