Review of antimalarial natural products

Malaria is still the very important parasitic disease in the world. Traditional medicines are used to treatmalaria on thousands of years and the sources of artemisinin and quinine derivatives with the high levels of drug resistance, the more cost of artemisinin based on combination therapies and spurious antimalarial drugs, traditional medicine is important and sustainable source of malaria is treatment of endemic areas. The discovery and use of natural compounds required for investigation of safety and efficacy previous to release into the market. By referring to some recent literatures, data were collected about plant used for the treatment of malaria, evaluation of plant extracts for anti-malarial activity, modes of the action of natural antimalarial agents, and recent research on antimalarial plants in Iran and other countries.