Genome-wide DNA methylation profiling of blood samples from patients with major depressive disorder: correlation with symptom heterogeneity
These findings indicate that the DNA methylation status of specific genes may correlate with the severity of MDD symptoms, and that genome-wide DNA methylation analysis of blood samples would be useful for clarifying the DNA methylation profiles related to symptom heterogeneity.
Authors
- Eri Arai (ORCID: https://orcid.org/0000-0002-0076-4823)
- Shinsuke Hidese (ORCID: https://orcid.org/0000-0001-7541-2075)
- Hiroshi Kunugi (ORCID: https://orcid.org/0000-0002-7209-3790)
- Yukiko Nagao
- Kotaro Hattori (ORCID: https://orcid.org/0000-0002-4411-2317)
- Mao Fujimoto (ORCID: https://orcid.org/0000-0002-2020-935X)
- Yae Kanai (ORCID: https://orcid.org/0000-0002-7904-9506)
- Shinichi Kameyama (ORCID: https://orcid.org/0000-0003-3854-5332)
- Ying Tian (ORCID: https://orcid.org/0000-0002-7683-5261)
Institutions
- Keio University (JP)
- National Center of Neurology and Psychiatry (JP)
- Center for Genomic Science (IT)
Publication Details
- Journal
- Journal of Psychiatry and Neuroscience
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1503/jpn.240126
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61