An efficient total synthesis of (+)-entecavir

An efficient asymmetric total synthesis of entecavir was achieved in 9 steps from rac -5. This work constitutes a robust basis for the development of a new step-economic and cost-effective process for the production of entecavir.

Authors

Caihong Zhu (ORCID: https://orcid.org/0000-0002-0272-2977)
Na Li (ORCID: https://orcid.org/0000-0003-2821-0547)
Yi Ma (ORCID: https://orcid.org/0000-0002-4125-9698)
Bingfeng Sun

Institutions

Nanjing Tech University (CN)

Publication Details

Journal: Organic Chemistry Frontiers
Published: 2025-01-01
DOI: https://doi.org/10.1039/d5qo00329f
Citations: 2
Primary Topic: HIV/AIDS drug development and treatment
Type: article
Field-Weighted Citation Impact: 2.79

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article

An efficient total synthesis of (+)-entecavir

Caihong Zhu, Na Li, Yi Ma, Bingfeng Sun

Jan 1, 2025

2 citations

Organic Chemistry Frontiers

HIV/AIDS drug development and treatment

2.79

article

An efficient total synthesis of (+)-entecavir

Caihong Zhu, Na Li, Yi Ma, Bingfeng Sun

January 1, 2025article en

2 citations

Abstract

Organic Chemistry FrontiersVol. 12(14)

Nanjing Tech University (CN)

Openalex Percentile: Top 11%

HIV/AIDS drug development and treatment

2.79

DOI Source OpenAlex

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An efficient total synthesis of (+)-entecavir — Caihong Zhu, Na Li, et al. · Organic Chemistry Frontiers (2025) | TGRS Research Map | TGRS