Aromatic compounds and their fascinating boron complexes as potential quorum sensing molecules
Abstract Aromatic compounds are widely distributed in the plant kingdom and, to a lesser extent, in the animal kingdom. Boron complexes are naturally produced by bacteria, fungi, and plants, playing significant roles in various biological processes. This review compiles existing knowledge on aromatic compounds containing vicinal hydroxyl groups (1,2‐diols) capable of forming diverse boron complexes. Boron‐containing complexes represent a fascinating group of substances whose biological significance and activity remain insufficiently explored. These complexes are of great interest not only in the chemical industry but also in medicine, pharmacology, and biotechnology. Notably, aromatic boronosteroids exhibit potent anticancer properties, while low‐molecular‐weight aromatic boron complexes demonstrate antibacterial activity. Some of these compounds function as quorum‐sensing inhibitors, interfering with bacterial communication and potentially serving as novel antimicrobial agents.
Authors
- Alexander Olegovich Terent'ev (ORCID: https://orcid.org/0000-0001-8018-031X)
- Valery M. Dembitsky (ORCID: https://orcid.org/0000-0002-4603-8704)
- S. V. Baranin (ORCID: https://orcid.org/0000-0003-3520-214X)
- M.E. Gursky
Institutions
- N.D. Zelinsky Institute of Organic Chemistry (RU)
Publication Details
- Journal
- Vietnam Journal of Chemistry
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/vjch.70013
- Citations
- 5
- Primary Topic
- Porphyrin and Phthalocyanine Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 2.59