An Account of Management of Patients of post-COVID Mucormycosis: A Surgical Perspective

Mucormycosis is a rare fatal fungal infection which has caused havoc in the present scenario of COVID-19 pandemic usually infecting post-COVID-19 recovered patients who were treated with corticosteroids or those who had ill regulated diabetes or immunocompromised states. The causative organism is a saprophytic fungus of the order mucorales and has a high affinity for blood vessels causing endothelial damage and thrombosis which results in necrosis of the affected tissues. Rhinocerebral mucormycosis is the most common infection being diagnosed in the current cases requiring the combined surgical approaches of an ENT Surgeon, a Maxillofacial surgeon and a Neurosurgeon. The disease may progress to involve the cranium thereby increasing the mortality rate. The first line of management in mucormycosis is antifungal therapy which may extend and also include surgical management by debridement/resection of the necrosed structures. In this article, we have reported a case series of 50 mucormycosis patients most of whom are post COVID, with the discussion of their demographics, affected structures, teeth mobility, blood sugar levels and neutrophil count with detailed description of the cases.

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Publication Details

Journal
The Traumaxilla
Published
2024-12-01
DOI
https://doi.org/10.1177/26323273251319753
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

An Account of Management of Patients of post-COVID Mucormycosis: A Surgical Perspective

Sam Khan, Shivani Sharma, Mohammed Haaris Khan, Geeta Singh
The Traumaxilla
Antifungal resistance and susceptibility
article

An Account of Management of Patients of post-COVID Mucormycosis: A Surgical Perspective

Sam Khan, Shivani Sharma, Mohammed Haaris Khan, Geeta Singh
article en

Abstract

Mucormycosis is a rare fatal fungal infection which has caused havoc in the present scenario of COVID-19 pandemic usually infecting post-COVID-19 recovered patients who were treated with corticosteroids or those who had ill regulated diabetes or immunocompromised states. The causative organism is a saprophytic fungus of the order mucorales and has a high affinity for blood vessels causing endothelial damage and thrombosis which results in necrosis of the affected tissues. Rhinocerebral mucormycosis is the most common infection being diagnosed in the current cases requiring the combined surgical approaches of an ENT Surgeon, a Maxillofacial surgeon and a Neurosurgeon. The disease may progress to involve the cranium thereby increasing the mortality rate. The first line of management in mucormycosis is antifungal therapy which may extend and also include surgical management by debridement/resection of the necrosed structures. In this article, we have reported a case series of 50 mucormycosis patients most of whom are post COVID, with the discussion of their demographics, affected structures, teeth mobility, blood sugar levels and neutrophil count with detailed description of the cases.

The TraumaxillaVol. 6(1-3)
Aligarh Muslim University (IN), Babu Banarasi Das University (IN), King George's Medical University (IN)
Openalex Percentile: Top 68%
Antifungal resistance and susceptibility
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