Sustainable Pharmaceutical Development Utilizing Vigna mungo Polymer Microbeads

This study explores the potential of Vigna mungo gum as a sustainable and innovative natural polymer for developing microbeads for the controlled delivery of vildagliptin, a widely used antidiabetic agent. Unlike conventional natural polymers, Vigna mungo gum offers unique biocompatibility, biodegradability, and an eco-friendly production process, distinguishing it as a superior candidate for drug delivery systems. Microbeads were prepared by combining Vigna mungo gum with sodium alginate and inducing gelation using calcium carbonate. Scanning electron microscopy (SEM) revealed a rough, porous microbead surface, advantageous for drug encapsulation and controlled release. Drug release studies demonstrated sustained release kinetics, highlighting the effectiveness of this formulation. These findings underscore the novelty of Vigna mungo gum as a promising platform for antidiabetic drug delivery, providing a sustainable alternative to existing polymer systems.

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Published
2025-04-02
DOI
https://doi.org/10.3390/engproc2024081014
Primary Topic
Graphene and Nanomaterials Applications
Type
article
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article

Sustainable Pharmaceutical Development Utilizing Vigna mungo Polymer Microbeads

Krishnaveni Manubolu, Raveesha Peeriga
Graphene and Nanomaterials Applications
article

Sustainable Pharmaceutical Development Utilizing Vigna mungo Polymer Microbeads

Krishnaveni Manubolu, Raveesha Peeriga
article en

Abstract

This study explores the potential of Vigna mungo gum as a sustainable and innovative natural polymer for developing microbeads for the controlled delivery of vildagliptin, a widely used antidiabetic agent. Unlike conventional natural polymers, Vigna mungo gum offers unique biocompatibility, biodegradability, and an eco-friendly production process, distinguishing it as a superior candidate for drug delivery systems. Microbeads were prepared by combining Vigna mungo gum with sodium alginate and inducing gelation using calcium carbonate. Scanning electron microscopy (SEM) revealed a rough, porous microbead surface, advantageous for drug encapsulation and controlled release. Drug release studies demonstrated sustained release kinetics, highlighting the effectiveness of this formulation. These findings underscore the novelty of Vigna mungo gum as a promising platform for antidiabetic drug delivery, providing a sustainable alternative to existing polymer systems.

Narayana Dental College and Hospital (IN)
Responsible consumption and production, Industry, innovation and infrastructure
Openalex Percentile: Top 94%
Graphene and Nanomaterials Applications
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