Interaction and verification of ferroptosis-related RNAs Rela and Stat3 in promoting sepsis-associated acute kidney injury
This study identified the significant roles of RNAs Rela and Stat3 in SA-AKI. The developed diagnostic model demonstrated improved accuracy in identifying SA-AKI, suggesting that these RNA markers may provide valuable insights into the pathophysiology of SA-AKI and enhance early diagnosis. These findings contribute to a better understanding of immune-related mechanisms underlying SA-AKI and may inform future therapeutic strategies.
Authors
- Yang Cao (ORCID: https://orcid.org/0000-0002-0058-614X)
- Yue Wang (ORCID: https://orcid.org/0000-0002-2719-287X)
- Yunlong Li
- Junbo Zheng (ORCID: https://orcid.org/0009-0002-0569-5764)
- Yansong Liu (ORCID: https://orcid.org/0000-0002-9618-5243)
- Hongliang Wang (ORCID: https://orcid.org/0000-0002-1407-0072)
Institutions
- Harbin Medical University (CN)
- Wright State University (US)
- Second Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Open Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1515/med-2025-1156
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00