ABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patients
This retrospective single-center study confirms an association between A and AB blood type with more severe COVID-19. While an underlying mechanism was not identified, the finding of higher adipsin levels in patients with type A/AB blood warrants further investigation in larger prospective studies.
Authors
- George Goshua (ORCID: https://orcid.org/0000-0002-1624-4427)
- Ryan L. Hoiland (ORCID: https://orcid.org/0000-0002-5657-0059)
- Sophie Stukas (ORCID: https://orcid.org/0000-0001-8819-8821)
- Luke Y. C. Chen (ORCID: https://orcid.org/0000-0002-9551-2951)
- Edward M. Conway (ORCID: https://orcid.org/0000-0003-0081-0305)
- Mypinder S. Sekhon (ORCID: https://orcid.org/0000-0002-4487-301X)
- Agnes Lee (ORCID: https://orcid.org/0000-0003-1915-6681)
Institutions
- Dalhousie University (CA)
- Yale New Haven Hospital (US)
- University of British Columbia (CA)
- Yale Cancer Center (US)
- University of British Columbia, Okanagan Campus (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1371/journal.pone.0320251
- Citations
- 1
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- VGH and UBC Hospital Foundation
- NOMIS Stiftung