Straightforward synthesis of diarylacetylenes from tetrachloroethylene using Kumada coupling reaction by Pd catalyst. Application to tri- and tetraarylethylenes

Abstract Pd-catalyzed Kumada coupling reaction of tetrachloroethylene and Grignard reagents was effective for the formation of diarylacetylenes as simple and convenient reaction, in which diarylacetylenes were successfully obtained in up to 82% yields and 14 examples were demonstrated. In addition, the current reaction was applicable for the straightforward synthesis of tri and tetra-substituted arylethylenes in good yields.