Elevated expression of microRNA-155, microRNA-383, and microRNA-9 in Iranian patients with polycystic ovary syndrome

Our findings suggest that miR-155, miR-383, and miR-9 are significantly upregulated in Iranian PCOS patients, highlighting their potential as biomarkers or therapeutic targets. However, no significant associations were found between the investigated SNPs and PCOS risk. Future studies with larger, multi-ethnic cohorts are warranted to validate these findings and explore the molecular mechanisms underlying the roles of these miRNAs in PCOS pathophysiology.

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Publication Details

Journal
Biochemistry and Biophysics Reports
Published
2025-04-02
DOI
https://doi.org/10.1016/j.bbrep.2025.101997
Citations
1
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
0.94
Controls
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article

Elevated expression of microRNA-155, microRNA-383, and microRNA-9 in Iranian patients with polycystic ovary syndrome

Hamed Afkhami, Kambiz Roshanaei, Nasrin Heidarieh, Maryam Faraji
1 citations
Biochemistry and Biophysics Reports
MicroRNA in disease regulation
0.94
article

Elevated expression of microRNA-155, microRNA-383, and microRNA-9 in Iranian patients with polycystic ovary syndrome

Hamed Afkhami, Kambiz Roshanaei, Nasrin Heidarieh, Maryam Faraji
article en
1 citations

Abstract

Our findings suggest that miR-155, miR-383, and miR-9 are significantly upregulated in Iranian PCOS patients, highlighting their potential as biomarkers or therapeutic targets. However, no significant associations were found between the investigated SNPs and PCOS risk. Future studies with larger, multi-ethnic cohorts are warranted to validate these findings and explore the molecular mechanisms underlying the roles of these miRNAs in PCOS pathophysiology.

Biochemistry and Biophysics ReportsVol. 42
Shahed University (IR), Qom Islamic Azad University (IR), Qom University of Medical Science and Health Services (IR)
Zero hunger
Openalex Percentile: Top 27%
MicroRNA in disease regulation
0.94
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