Rh( <scp>iii</scp> )-catalyzed base-free α-arylation of iodonium ylides with arylboronic acids: modular synthesis of 5-aryl barbituric acids

The first Suzuki-type cross-coupling of iodonium ylides to access medically important 5-aryl barbituric acids has developed. This general approach exhibits mild reaction conditions, operational simplicity, and robustness against moisture and air.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d5qo00259a
Citations
2
Primary Topic
Catalytic C–H Functionalization Methods
Type
article
Field-Weighted Citation Impact
1.87
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article

Rh( iii )-catalyzed base-free α-arylation of iodonium ylides with arylboronic acids: modular synthesis of 5-aryl barbituric acids

Shaoyu Mai, Huaming Tao, Linxiang Zhao, Mengling He et al.
2 citations
Organic Chemistry Frontiers
Catalytic C–H Functionalization Methods
1.87
article

Rh( iii )-catalyzed base-free α-arylation of iodonium ylides with arylboronic acids: modular synthesis of 5-aryl barbituric acids

Shaoyu Mai, Huaming Tao, Linxiang Zhao, Mengling He, S. X. CAI, Nursemanguli Baiheti
article en
2 citations

Abstract

The first Suzuki-type cross-coupling of iodonium ylides to access medically important 5-aryl barbituric acids has developed. This general approach exhibits mild reaction conditions, operational simplicity, and robustness against moisture and air.

Organic Chemistry FrontiersVol. 12(15)
Southern Medical University (CN)
Openalex Percentile: Top 17%
Catalytic C–H Functionalization Methods
1.87
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Rh( <scp>iii</scp> )-catalyzed base-free α-arylation of iodonium ylides with arylboronic acids: modular synthesis of 5-aryl barbituric acids — Shaoyu Mai, Huaming Tao, et al. · Organic Chemistry Frontiers (2025) | TGRS Research Map | TGRS