Rh( <scp>iii</scp> )-catalyzed base-free α-arylation of iodonium ylides with arylboronic acids: modular synthesis of 5-aryl barbituric acids
The first Suzuki-type cross-coupling of iodonium ylides to access medically important 5-aryl barbituric acids has developed. This general approach exhibits mild reaction conditions, operational simplicity, and robustness against moisture and air.
Authors
- Shaoyu Mai (ORCID: https://orcid.org/0000-0002-9318-7606)
- Huaming Tao (ORCID: https://orcid.org/0000-0002-4799-1345)
- Linxiang Zhao (ORCID: https://orcid.org/0009-0000-5239-8135)
- Mengling He
- S. X. CAI
- Nursemanguli Baiheti
Institutions
- Southern Medical University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00259a
- Citations
- 2
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.87