Contorted acene ribbons for stable and ultrasensitive neural probes

Organic materials that conduct both electrons and ions are integral to implantable bioelectronics because of their conformable nature. There is a dearth of these materials that are highly sensitive to cations, which are the majority ions on the surface of neurons. This manuscript offers a solution using an extended ribbon structure that is defect-free, providing high electronic mobility along its fused backbone, while the edge structure of these ribbons promotes high ionic conductivity. We incorporated these mixed ion/electron conductors into neural probes and implanted them in a rodent brain where they offer a suite of useful properties: high cation sensitivity, stability over several weeks after implantation, and biocompatibility. These materials represent an innovative class of implantable biosensors.

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Publication Details

Journal
Science Advances
Published
2025-04-02
DOI
https://doi.org/10.1126/sciadv.adu2356
Citations
1
Primary Topic
Conducting polymers and applications
Type
article
Field-Weighted Citation Impact
0.61
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Contorted acene ribbons for stable and ultrasensitive neural probes

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Contorted acene ribbons for stable and ultrasensitive neural probes

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article en
1 citations

Abstract

Organic materials that conduct both electrons and ions are integral to implantable bioelectronics because of their conformable nature. There is a dearth of these materials that are highly sensitive to cations, which are the majority ions on the surface of neurons. This manuscript offers a solution using an extended ribbon structure that is defect-free, providing high electronic mobility along its fused backbone, while the edge structure of these ribbons promotes high ionic conductivity. We incorporated these mixed ion/electron conductors into neural probes and implanted them in a rodent brain where they offer a suite of useful properties: high cation sensitivity, stability over several weeks after implantation, and biocompatibility. These materials represent an innovative class of implantable biosensors.

Science AdvancesVol. 11(14)
Brookhaven National Laboratory (US), University of California, Irvine (US), Cornell University (US), Irvine University (US), Columbia University (US)
Openalex Percentile: Top 38%
Conducting polymers and applications
0.61
DOIOpen Access PDFOpenAlex
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Contorted acene ribbons for stable and ultrasensitive neural probes — Si Tong Bao, Ashutosh Garudapalli, et al. · Science Advances (2025) | TGRS Research Map | TGRS