Astragaloside IV accelerates hematopoietic reconstruction by improving the AMPK/PGC1α-mediated mitochondrial function in hematopoietic stem cells
AS-IV accelerates hematopoietic reconstruction following radiation injury via activation of the AMPK/PGC1α signaling pathway, which enhances HSC mitochondrial function.
Authors
- F Huang (ORCID: https://orcid.org/0000-0002-6828-3399)
- Qibing Mei
- Anguo Wu (ORCID: https://orcid.org/0000-0002-9850-7576)
- Xiaogang Zhou (ORCID: https://orcid.org/0000-0002-2574-3973)
- Yueying Zeng
- Dalian Qin (ORCID: https://orcid.org/0000-0002-1235-7328)
- Long Wang (ORCID: https://orcid.org/0000-0002-2733-7370)
- Wanqi Xu (ORCID: https://orcid.org/0009-0003-2077-0037)
- Jianming Wu (ORCID: https://orcid.org/0000-0002-6136-7469)
- Jiesi Luo
- Ling Zhang (ORCID: https://orcid.org/0000-0001-5850-6811)
Institutions
- Southwest Medical University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1186/s13020-025-01092-3
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shenyang Science and Technology Bureau
- Sichuan Province Science and Technology Support Program