Multifunctional nanoplatform for tumor chemodynamic and self-amplified photodynamic cascade therapy
5-ALA@Zn-CuTz@PM NPs effectively enhance PDT efficacy through selective tumor targeting and HO-1 inhibition while simultaneously leveraging CDT for additional tumor suppression. The combined PDT/CDT strategy demonstrated superior therapeutic outcomes, highlighting the potential of this nanoplatform as a promising approach for breast cancer treatment.
Authors
- Haifeng Qi (ORCID: https://orcid.org/0000-0001-9387-1195)
- M. Yan (ORCID: https://orcid.org/0000-0002-4301-5793)
- Tong Xu
- Xiaoling Luo (ORCID: https://orcid.org/0009-0004-9640-7899)
- Wei Han (ORCID: https://orcid.org/0000-0002-8578-6780)
- Ting Wu
- Yin Ding (ORCID: https://orcid.org/0009-0002-7348-4248)
Institutions
- Nanjing Agricultural University (CN)
- Nanjing University of Chinese Medicine (CN)
- Nanjing Tech University (CN)
- Stomatology Hospital (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1016/j.jare.2025.03.056
- Citations
- 2
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 1.35