Multi-approach analysis reveals the mechanism by which Shugan Xiaozhi decoction protects against metabolic dysfunction-associated steatohepatitis
SGXZ decoction does have a therapeutic effect on MASH, and its mechanism may be related to its regulation of p53/ SLC7A11/GPX4 pathway to reduce ferroptosis.
Authors
- Xia Jiang
- Lidan Luo
- Qibiao Wu (ORCID: https://orcid.org/0000-0002-1670-1050)
- Ruili Du
- Jie Xu (ORCID: https://orcid.org/0000-0003-2435-0382)
- Shuai Wang (ORCID: https://orcid.org/0000-0002-9787-7591)
- Chunmei Zhang (ORCID: https://orcid.org/0000-0002-0882-9361)
- Jiahui Liu (ORCID: https://orcid.org/0009-0001-8829-4490)
- Weichao Zhong
- Guangdong Tong
Institutions
- Macau University of Science and Technology (MO)
- Guangzhou University of Chinese Medicine (CN)
- Henan University of Science and Technology (CN)
- University of Macau (MO)
- Southwest Medical University (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1016/j.phymed.2025.156712
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00